KMID : 0386320080410020017
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Korean Leprosy Bulletin 2008 Volume.41 No. 2 p.17 ~ p.22
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Hydoroxocobalamin (Vitamin B12) Effects on Nerve Function Impairments in Leprosy
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Lee Kyung-Duk
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Abstract
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95 patients in Sorokdo national hospital injected 1-5mg Hydroxocobalamin (5mg/2ml/1ample) in 5-7 days/week, duration 6.4 months, average age 71.6 years old. Effects are 1) softening of hand movement(22/95), early effect, 2) improving of motor function (8/95) 3) sensory function(8/95) 4) sweating (3/95) 5) neuropathic pain and headache(neuralgia-like) (7/95) 6) jaw and hand tremor (7/95) 7) no response (41/95) 8) side effect (1/95) Leprosy is demyelinating peripheral neuropathy, Vitamin B12 effects on myelin, but unkown it¡¯s mechnism. Vitamin B12 improve nerve function impairments in leprosy, especially neuropathic pain and tremor, which lead to deformities and disabilities.
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KEYWORD
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Leprosy, Nerve function impairment, Neuralgia, Tremor, Hydoroxocobalamin (Vitamin B12)
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